Guidelines and Key Manuscripts

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Guidelines and Key Manuscripts

Explanatory Note: The material listed on this page has been identified as important references that may be useful for the study of pathology by a variety of sources (e.g., test development committee members, ABPath Cooperating Society members, etc.).  The inclusion of material on this site constitutes recommendations of material that may be beneficial to the trainees and practitioners in various subspecialties in Pathology and Laboratory Medicine. Inclusion does not represent an endorsement by the American Board of Pathology and exclusion should not be viewed as disapproval. It is simply not possible to include all relevant material. Textbooks are purposefully not included, with a few exceptions (e.g., WHO documents).

Some guidance documents may be more relevant for fellow-level trainees than pathology residents; review of these recommendations with individual course directors is recommended. If there is a conspicuous absence of an important guideline or manuscript thought to be key for resident/fellow learning, please contact ABPath at Questions@abpath.org. These recommendations will be reviewed by our Test Development and Advisory Committees for potential inclusion.

Anatomic Pathology (AP)

General AP
  1. CAP Cancer Protocol Templates (https://www.cap.org/protocols-and-guidelines/cancer-reporting-tools/cancer-protocol-templates)

  2. NCCN guidelines (https://www.nccn.org/guidelines/category_1)

  3. CAP Laboratory Accreditation Checklists https://www.cap.org/laboratory-improvement/accreditation/accreditation-checklists
General AP with Subspecialty Areas Represented

    Hematopathology – AP

    1. World Health Organization. WHO Classification of Tumours: Haematolymphoid Tumours. 5th edition. Lyon, France: International Agency for Research on Cancer, 2024.

    2. The International Consensus Classification of Myeloid and Lymphoid Neoplasms. 1st ed. Arber DA, Borowitz MJ, Cook JR, de Leval L, Goodlad JR, Hasserjian RP, et al., editors. Philadelphia: Wolters Kluwer; 2025.

    3. Foucar K, Bagg A, Bueso-Ramos CE, George T, Hasserjian RP, His ED, et al. Guide to the Diagnosis of Myeloid Neoplasms: A Bone Marrow Pathology Group Approach. Am J Clin Pathol. 2023;160(4):365-93.

    4. Dohner H. Wei AH, Appelbaum FR, Craddock C, DiNardo CD, Dombret H, et al. Diagnosis and management of AML in adults: 2022 recommendations from an international expert panel on behalf of the ELN. Blood. 2022;140(12):1345-77.

    5. Kavus, H., Ding, Y., & Dhesi, M. (2023). Updates in Immunohistochemistry for Hematopoietic and Lymphoid Neoplasms. Archives of pathology & laboratory medicine, 10.5858/arpa.2022-0465-RA. Advance online publication. https://doi.org/10.5858/arpa.2022-0465-RA
    Autopsy & Forensic Pathology
    1. NAME Autopsy Standards, Forensic Autopsy (memberclicks.net)

    2. Death Certification for AP, https://www.cdc.gov/nchs/data/nvss/handbook/2023-physicians-mcod-handbook.pdf

    3. A Guide for Manner of Death Classification, https://name.memberclicks.net/assets/docs/MANNEROFDEATH.pdf

    4. NAME Public Position Papers and Statements, https://www.thename.org/name-public-position-papers-and-statements
    Breast


    1. CAP/ASCO HER2 Guidelines:
      https://meridian.allenpress.com/aplm/article/147/9/993/493531/Human-Epidermal-Growth-Factor-Receptor-2-Testing

    2. Society of Surgical Oncology–American Society for Radiation Oncology–American Society for Clinical Oncology Consensus Guidelines: https://pubmed.ncbi.nlm.nih.gov/24516019/

    3. Allison, K. H., Hammond, M. E. H., Dowsett, M., McKernin, S. E., Carey, L. A., Fitzgibbons, P. L., … & Wolff, A. C. (2020). Estrogen and progesterone receptor testing in breast cancer: American Society of Clinical Oncology/College of American Pathologists guideline update. Archives of pathology & laboratory medicine, 144(5), 545-563.

    4. WHO Classification of Tumours Editorial Board. Breast tumours. Lyon (France): International Agency for Research on Cancer; 2019. (WHO classification of tumours series, 5th ed.; vol. 2). https://publications.iarc.fr/581.

    5. Tan, P. H., Ellis I., Allison K., Brogi E., Fox S. B., Lakhani S., Lazar A. J., Morris E. A., Sahin A., Salgado R., Sapino A., Sasano H., Schnitt S., Sotiriou C., van Diest P., White V. A., Lokuhetty D., Cree, I. A. & for the WHO Classification of Tumours Editorial Board. (2020) Histopathology 77, 181–185. https://doi.org/10.1111/his.14091 The 2019 World Health Organization classification of tumours of the breast
    Cardiovascular System
    1. Billingham, M., & Kobashigawa, J. A. (2005). The Revised ISHLT Heart Biopsy Grading Scale. The Journal of Heart and Lung Transplantation, 24(11), 1709. https://doi.org/10.1016/j.healun.2005.03.018

    2. ISSVA classification of vascular anomalies ©2018 International Society for the Study of Vascular Anomalies https://www.issva.org/classification
    Cytopathology

    Standardized Terminology- Reporting Systems

    1. Faquin WC, Rossi ED, Baloch Z, Barkan GA, Foschini MP, Kurtycz DF, Pusztaszeri M, Vielh P (Eds). The Milan System for Reporting Salivary Gland Cytology. 2nd Edition. Springer; 2023

    2. Ali SA, VanderLaan PA (Eds). The Bethesda System for Reporting Thyroid Cytology. 3rd Edition. Springer; 2023

    3. Wojcik, E. M., Kurtycz, D. F., & Rosenthal, D. L. (Eds.). The Paris system for reporting urinary cytology. 2nd Edition Springer; 2022.

    4. Crothers B., Baloch Z., Chandra A., Kurtycz D., Schmitt F. (Eds). The International System for Reporting Serous Fluid Cytopathology: Introduction and Overview of Diagnostic Terminology and Reporting. Springer; 2020.

    5. Field AS, Raymond WA, Schmitt F. The International Academy of Cytology Yokohama System for Reporting Breast Fine Needle Aspiration Biopsy Cytopathology. Springer, 2020.

    6. Nayar R., Wilbur DC.(Eds). The Bethesda System for Reporting Cervical Cytology. Definitions, criteria, and explanatory notes. 3rd Edition. New York: Springer; 2015.

    7. Darragh TM, Colgan TJ, Cox JT, et al. The Lower Anogenital Squamous Terminology Standardization Project for HPV-Associated Lesions: background and consensus recommendations from the College of American Pathologists and the American Society for Colposcopy and Cervical Pathology. Arch Pathol Lab Med. 2012 Oct;136(10):1266-97.

    8. WHO Reporting System for Lung Cytopathology IAC-IARC-WHO Cytopathology Reporting Systems, 1st Edition. 2022. https://tumourclassification.iarc.who.int

    9. WHO Reporting System for Pancreaticobiliary Cytopathology IAC-IARC-WHO Cytopathology Reporting Systems, 1st Edition, 2022. https://publications.iarc.fr/Book-And-Report-Series/Iac-Iarc-Who-Cytopathology-Reporting-Systems


    10. WHO Reporting System for Lymph Node, Spleen, and Thymus Cytopathology. 1st Edition, 2025. https://tumourclassification.iarc.who.int/chaptercontent/49/155

    Pathology Guidelines

    1. Collection and Handling of Thoracic Small Biopsy and Cytology Specimens for Ancillary Studies, 2020. CAP Pathology and Laboratory Quality Center for Evidence-based Guidelines. https://www.cap.org/protocols-and-guidelines/current-cap-guidelines/collection-and-handling-of-thoracic-specimens

    2. Principles of Analytic Validation of Immunohistochemical Assays: Guideline Update, 2024. CAP Pathology and Laboratory Quality Center for Evidence Guidelines. https://www.cap.org/protocols-and-guidelines/cap-guidelines/current-cap-guidelines/principles-of-analytic-validation-of-immunohistochemical-assays

    3. Human Papillomavirus Testing in Head and Neck Carcinomas CAP Guideline Update.  Arch Pathol Lab Med. doi: 10.5858/arpa.2024-0388-CP

    Clinical Management Guidelines

    1. Cervical cancer screening for individuals at average risk: 2020 guideline update from the American Cancer Society. https://doi.org/10.3322/caac.21628

    2. 2019 ASCCP Risk-Based Management Consensus Guidelines for Abnormal Cervical Cancer Screening Tests and Cancer Precursors. J Low Genit Tract Dis 2020;24: 102–131

    3. Clarke MA, Wentzensen N, Perkins RB, Garcia F, Arrindell D, Chelmow D, Cheung LC, Darragh TM, Egemen D, Guido R, Huh W, Locke A, Lorey TS, Nayar R, Risley C, Saslow D, Smith RA, Unger ER, Massad LS. Enduring Consensus Cervical Cancer Screening and Management Guidelines Committee. Recommendations for Use of p16/Ki67 Dual Stain for Management of Individuals Testing Positive for Human Papillomavirus. J Low Genit Tract Dis. 2024 Apr 1;28(2):124-130. PMID: 38446575.

    4. Massad S, et al. Recommendations for applying results of extended genotyping to management of individuals with positive cervicovaginal human papillomavirus test results: An Enduring Guidelines effort. Submitted (August 2024)

    5. Haugen BR, Alexander EK, Bible KC, et al. 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer. Thyroid. 2016 Jan;26(1):1-133.

    Cytopathology Lab Management and Accreditation

    1. Nayar R, Barkan GA, Benedict C, Booth C, Chhieng DC, Mody D, Siddiqui MT, Tabatabai LZ, Johnson R. Laboratory management curriculum for cytopathology subspecialty training. J Am Soc Cytopathol. 2018 Mar-Apr;7(2):61-78. doi: 10.1016/j.jasc.2017.12.003. Epub 2017 Dec 15. PMID: 31043255.

    2. CAP Cytopathology and All Common checklists @ https://www.cap.org/laboratory-improvement/accreditation/accreditation-checklists

    Miscellaneous

    1. Nayar R, Barkan GA, Benedict C, et al. Laboratory management curriculum for cytopathology subspecialty training. J Am Soc Cytopathol. 2018 Mar-Apr;7(2):61-78.

    2. Human Papillomavirus Vaccination for Adults: Updated Recommendations of the Advisory Committee on Immunization Practices. MMWR, August 16, 2019, Vol 68(32);698-702.

    3. Salazar KL, Duhon DJ, Olsen R, Thrall M. A review of the FDA-approved molecular testing platforms for human papillomavirus. Journal of the American Society of Cytopathology, 8(5), 2019, 284-292.



    Dermatopathology
    1. WHO Classification of Tumours Editorial Board. Skin tumours. Lyon (France): International Agency for Research on Cancer; forthcoming. (WHO classification of tumours series, 5th ed.; vol. 12). https://tumourclassification.iarc.who.int/chapters/64

    2. AUC Committee Members; Fung et al. Appropriate use criteria for ancillary diagnostic testing in dermatopathology: New recommendations for 11 tests and 220 clinical scenarios from the American Society of Dermatopathology Appropriate Use Criteria Committee. J Cutan Pathol. 2022 Mar;49(3):231-245. doi: 10.1111/cup.14135. Epub 2021 Oct 19. PMID: 34536035.

    3. Christensen RE, et al. Dermatopathologic features of cutaneous squamous cell carcinoma and actinic keratosis: Consensus criteria and proposed reporting guidelines. J Am Acad Dermatol. 2023 Jun;88(6):1317-1325. doi: 10.1016/j.jaad.2022.12.057. Epub 2023 Feb 24. PMID: 36841336.

    4. Kempf W., Mitteldorf C., Cerroni L., Willemze R., Berti E., Guenova E., Scarisbrick JJ, Battistella M. Classifications of cutaneous lymphomas and lymphoproliferative disorders: An update from the EORTC cutaneous lymphoma histopathology group. J Eur Acad Dermatol Venereol. 2024 Apr 6. doi: 10.1111/jdv.19987. Epub ahead of print. PMID: 38581201.

    5. Saleem A., Narala S., Raghavan SS. Immunohistochemistry in melanocytic lesions: Updates with a practical review for pathologists. Semin Diagn Pathol. 2022 Jul;39(4):239-247. doi: 10.1053/j.semdp.2021.12.003. Epub 2022 Jan 1. PMID: 35016807.

    6. Busam K.J., Judge M.J., Bichakjian C.K., Coit D., Kutzner H., Requena L., Scolyer R.A., Stefanato C.M., Wood B.A., Walsh N.M.. Dataset for the Reporting of Merkel Cell Carcinoma: Recommendations From the International Collaboration on Cancer Reporting (ICCR). Am J Surg Pathol. 2022 Nov 1;46(11):1583-1591. doi: 10.1097/PAS.0000000000001959. Epub 2022 Aug 25. PMID: 36001458.

    7. Chukwudebe O, Brown RA. Immunohistochemical and molecular updates in cutaneous soft tissue neoplasms. Semin Diagn Pathol. 2022 Jul;39(4):257-264. doi: 10.1053/j.semdp.2022.02.004. Epub 2022 Feb 19. PMID: 35305853.

    8. Kim RH, Brinster NK. Practical Direct Immunofluorescence. Am J Dermatopathol. 2020 Feb;42(2):75-85. doi: 10.1097/DAD.0000000000001516. PMID: 31990699.

    9. Abate MS, Battle LR, Emerson AN, Gardner JM, Shalin SC. Dermatologic Urgencies and Emergencies: What Every Pathologist Should Know. Arch Pathol Lab Med. 2019 Aug;143(8):919-942. doi: 10.5858/arpa.2018-0239-RA. Epub 2019 Feb 20. PMID: 30785787.

    10. Dany M, Fischer AS, Pei S, Rubin AI. Updates on the Pathology and Management of Nail Unit Tumors and Dermatoses. Surg Pathol Clin. 2021 Jun;14(2):327-339. doi: 10.1016/j.path.2021.03.006. PMID: 34023109.

    11. Yeh I. Melanocytic naevi, melanocytomas and emerging concepts. Pathology. 2023 Mar;55(2):178-186. doi: 10.1016/j.pathol.2022.12.341. Epub 2022 Dec 27. PMID: 36642570.

    12. Fischer GM, Papke DJ Jr. Gene fusions in superficial mesenchymal neoplasms: Emerging entities and useful diagnostic adjuncts. Semin Diagn Pathol. 2023 Jul;40(4):246-257. doi: 10.1053/j.semdp.2023.04.014. Epub 2023 Apr 25. PMID: 37156707.

    13. American Society of Dermatopathology Appropriate Use Criteria https://www.asdp.org/ASDP/ASDPWeb/Education/Dermpath-Appropriate-Use-Criteria.aspx?hkey=6268caf0-05d2-4b84-8252-09d2583c993c
    Digestive System
    1. WHO Classification of Tumours Editorial Board. Digestive system tumours. Lyon (France): International Agency for Research on Cancer; 2019. (WHO classification of tumours series, 5th ed.; vol. 1). https://publications.iarc.fr/579.
    Endocrine System
    1. WHO Classification of Tumours Editorial Board. Endocrine and neuroendocrine tumours. Lyon (France): International Agency for Research on Cancer; 2022. (WHO classification of tumours series, 5th ed.; vol. 10). https://tumourclassification.iarc.who.int/chapters/53

    2. Rindi, G., Mete, O., Uccella, S., Basturk, O., La Rosa, S., Brosens, L. A., … & Asa, S. L. (2022). Overview of the 2022 WHO classification of neuroendocrine neoplasms. Endocrine Pathology, 33(1), 115-154.
    Female Genital System
    1. WHO Classification of Tumours Editorial Board. Female genital tumours. Lyon (France): International Agency for Research on Cancer; 2020. (WHO classification of tumours series, 5th ed.; vol. 4). https://publications.iarc.fr/592.

    2. Sisodia, R. C., & Del Carmen, M. G. (2022). Lesions of the Ovary and Fallopian Tube. The New England Journal of Medicine, 387(8), 727–736. https://www.nejm.org/doi/10.1056/NEJMra2108956

    3. American Cancer Society 2020 guidelines for cervical cancer screening: https://www.cancer.org/cancer/types/cervical-cancer/detection-diagnosis-staging/cervical-cancer-screening-guidelines.html#:~:text=Cervical%20cancer%20testing%20(screening)%20should,test%20alone%20every%203%20years.

    4. 2019 Risk-Based Management Consensus Guidelines: https://www.asccp.org/Assets/b2263c88-ec67-4ab0-9f07-6f112e76f8d7/637269576182030000/2019-asccp-risk-based-management-consensus-3-5-pdf
    Head & Neck
    1. WHO Classification of Tumours Editorial Board. Head and neck tumours. Lyon (France): International Agency for Research on Cancer; forthcoming. (WHO Classification of Tumours series, 5th ed.; vol. 9). https://publications.iarc.fr.

    2. Lewis, J. S., Beadle, B., Bishop, J. A., Chernock, R. D., Colasacco, C., Kalicanin, T., Krane, J. F., Lacchetti, C., Moncur, J. T., Rocco, J. W., Schwartz, M. R., Seethala, R. R., & Faquin, W. C. (2025). Human Papillomavirus Testing in Head and Neck Carcinomas: Guideline Update. Archives of Pathology & Laboratory Medicine. https://doi.org/10.5858/arpa.2024-0388-CP
    Hematopathology
    1. World Health Organization. WHO Classification of Tumours: Haematolymphoid Tumours. 5th edition. Lyon, France: International Agency for Research on Cancer, 2024.

    2. The International Consensus Classification of Myeloid and Lymphoid Neoplasms. 1st ed. Arber DA, Borowitz MJ, Cook JR, de Leval L, Goodlad JR, Hasserjian RP, et al., editors. Philadelphia: Wolters Kluwer; 2025.

    3. Foucar K, Bagg A, Bueso-Ramos CE, George T, Hasserjian RP, His ED, et al. Guide to the Diagnosis of Myeloid Neoplasms: A Bone Marrow Pathology Group Approach. Am J Clin Pathol. 2023;160(4):365-93.

    4. Dohner H. Wei AH, Appelbaum FR, Craddock C, DiNardo CD, Dombret H, et al. Diagnosis and management of AML in adults: 2022 recommendations from an international expert panel on behalf of the ELN. Blood. 2022;140(12):1345-77.

    5. Kavus, H., Ding, Y., & Dhesi, M. (2023). Updates in Immunohistochemistry for Hematopoietic and Lymphoid Neoplasms. Archives of pathology & laboratory medicine, 10.5858/arpa.2022-0465-RA. Advance online publication. https://doi.org/10.5858/arpa.2022-0465-RA

    Male Genital System
    1. WHO Classification of Tumours Editorial Board. Urinary and male genital tumours. Lyon (France): International Agency for Research on Cancer; 2022. (WHO classification of tumours series, 5th ed.; vol. 8). https://publications.iarc.fr/610.
    Molecular Genetic Pathology
    1. Dungan, J. S., Klugman, S., Darilek, S., Malinowski, J., Akkari, Y. M., Monaghan, K. G., … & ACMG Board of Directors. (2023). Noninvasive prenatal screening (NIPS) for fetal chromosome abnormalities in a general-risk population: An evidence-based clinical guideline of the American College of Medical Genetics and Genomics (ACMG). Genetics in Medicine, 25(2), 100336. doi: https://doi.org/10.1016/j.gim.2022.11.004

    2. Seaver, L. H., Khushf, G., King, N. M., Matalon, D. R., Sanghavi, K., Vatta, M., … & Ethical and Legal Issues Committee. (2022). Points to consider to avoid unfair discrimination and the misuse of genetic information: A statement of the American College of Medical Genetics and Genomics (ACMG). Genetics in Medicine, 24(3), 512-520. doi: https://doi.org/10.1016/j.gim.2021.11.002

    3. Manickam, K., McClain, M. R., Demmer, L. A., Biswas, S., Kearney, H. M., Malinowski, J., … & Hisama, F. M. (2021). Exome and genome sequencing for pediatric patients with congenital anomalies or intellectual disability: an evidence-based clinical guideline of the American College of Medical Genetics and Genomics (ACMG). Genetics in Medicine, 23(11), 2029-2037. https://doi.org/10.1038/s41436-021-01242-6

    4. Antonio C. Wolff, Mark R. Somerfield, Mitchell Dowsett, M. Elizabeth H. Hammond, Daniel F. Hayes, Lisa M. McShane, Thomas J. Saphner, Patricia A. Spears, Kimberly H. Allison; Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: American Society of Clinical Oncology–College of American Pathologists Guideline Update. Arch Pathol Lab Med 1 September 2023; 147 (9): 993–1000. doi: https://doi.org/10.5858/arpa.2023-0950-SA

    5. Bartley, A. N., Mills, A. M., Konnick, E., Overman, M., Ventura, C. B., Souter, L., … & Broaddus, R. R. (2022). Mismatch repair and microsatellite instability testing for immune checkpoint inhibitor therapy: guideline from the College of American Pathologists in collaboration with the Association for Molecular Pathology and Fight Colorectal cancer. Archives of pathology & laboratory medicine, 146(10), 1194-1210. https://doi.org/10.5858/arpa.2021-0632-CP

    6. Brat, D. J., Aldape, K., Bridge, J. A., Canoll, P., Colman, H., Hameed, M. R., … Perry, A. (2022). Molecular Biomarker Testing for the Diagnosis of Diffuse Gliomas. Archives of Pathology & Laboratory Medicine, 146(5), 547–574. https://doi.org/10.5858/arpa.2021-0295-cp.

    7. Bartley, A. N., Washington, M. K., Ventura, C. B., Ismaila, N., Colasacco, C., Benson, A. B., … Ajani, J. A. (2016). HER2 Testing and Clinical Decision Making in Gastroesophageal Adenocarcinoma: Guideline From the College of American Pathologists, American Society for Clinical Pathology, and American Society of Clinical Oncology. Archives of Pathology & Laboratory Medicine, 140(12), 1345–1363. https://doi.org/10.5858/arpa.2016-0331-CP

    8. Li, M. M., Datto, M., Duncavage, E. J., Kulkarni, S., Lindeman, N. I., Roy, S., … Nikiforova, M. N. (2017). Standards and Guidelines for the Interpretation and Reporting of Sequence Variants in Cancer. The Journal of Molecular Diagnostics, 19(1), 4–23. https://doi.org/10.1016/j.jmoldx.2016.10.002

    9. Li, M. M., Cottrell, C. E., Mrudula Pullambhatla, Roy, S., Temple-Smolkin, R. L., Turner, S. A., … Vnencak-Jones, C. L. (2023). Assessments of Somatic Variant Classification Using the Association for Molecular Pathology/American Society of Clinical Oncology/College of American Pathologists Guidelines. The Journal of Molecular Diagnostics, 25(2), 69–86. https://doi.org/10.1016/j.jmoldx.2022.11.002

    10. Crooks, K., Farwell, K. D., Mandelker, D., Avni Santani, Schmidt, R. J., Temple-Smolkin, R. L., & Lincoln, S. E. (2023). Recommendations for Next-Generation Sequencing Germline Variant Confirmation (Vol. 25, pp. 411–427). https://doi.org/10.1016/j.jmoldx.2023.03.012

    11. Burd, E. M. (2010). Validation of Laboratory-Developed Molecular Assays for Infectious Diseases. Clinical Microbiology Reviews, 23(3), 550–576. https://doi.org/10.1128/cmr.00074-09

    12. Jennings, L. J., Arcila, M. E., Corless, C., Kamel-Reid, S., Lubin, I. M., Pfeifer, J., … Nikiforova, M. N. (2017). Guidelines for Validation of Next-Generation Sequencing-Based Oncology Panels: A Joint Consensus Recommendation of the Association for Molecular Pathology and College of American Pathologists. The Journal of Molecular Diagnostics : JMD, 19(3), 341–365. https://doi.org/10.1016/j.jmoldx.2017.01.011

    13. Roy, S., Coldren, C., Karunamurthy, A., Kip, N. S., Klee, E. W., Lincoln, S. E., … Carter, A. B. (2018). Standards and Guidelines for Validating Next-Generation Sequencing Bioinformatics Pipelines: A Joint Recommendation of the Association for Molecular Pathology and the College of American Pathologists. The Journal of Molecular Diagnostics: JMD, 20(1), 4–27. https://doi.org/10.1016/j.jmoldx.2017.11.003

    14. Deignan, J. L., Gregg, A. R., Grody, W. W., Guo, M. H., Kearney, H., Monaghan, K. G., … Ziats, C. (2023). Updated recommendations for CFTR carrier screening: A position statement of the American College of Medical Genetics and Genomics (ACMG). Genetics in Medicine, 100867. https://doi.org/10.1016/j.gim.2023.100867

    15. Green, R. C., Berg, J. S., Grody, W. W., Kalia, S. S., Korf, B. R., Martin, C. L., … Biesecker, L. G. (2013). ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing. Genetics in Medicine, 15(7), 565–574. https://doi.org/10.1038/gim.2013.73

    16. ACMG SF v3.3 list for reporting of secondary findings in clinical exome and genome sequencing: A policy statement of the American College of Medical Genetics and Genomics (ACMG) PMID: 40568962

    17. Masson, E., Zou, W.-B., Génin, E., Cooper, D. N., Le Gac, G., Fichou, Y., … Chen, J.-M. (2022). Expanding ACMG variant classification guidelines into a general framework. Human Genomics, 16(1). https://doi.org/10.1186/s40246-022-00407-x

    18. HGVS Nomenclature: https://hgvs-nomenclature.org/stable/

    19. Sepulveda, A. R., Hamilton, S. R., Allegra, C. J., Grody, W., Cushman-Vokoun, A. M., Funkhouser, W. K., Kopetz, S. E., Lieu, C., Lindor, N. M., Minsky, B. D., Monzon, F. A., Sargent, D. J., Singh, V. M., Willis, J., Clark, J., Colasacco, C., Rumble, R. B., Temple-Smolkin, R., Ventura, C. B., & Nowak, J. A. (2017). Molecular Biomarkers for the Evaluation of Colorectal Cancer. In The Journal of Molecular Diagnostics (Vol. 19, Issue 2, pp. 187–225). Elsevier BV. https://doi.org/10.1016/j.jmoldx.2016.11.001 (Update in Progress)

    20. Lindeman, N. I., Cagle, P. T., Aisner, D. L., Arcila, M. E., Beasley, M. B., Bernicker, E. H., Colasacco, C., Dacic, S., Hirsch, F. R., Kerr, K., Kwiatkowski, D. J., Ladanyi, M., Nowak, J. A., Sholl, L., Temple-Smolkin, R., Solomon, B., Souter, L. H., Thunnissen, E., Tsao, M. S., … Yatabe, Y. (2018). Updated Molecular Testing Guideline for the Selection of Lung Cancer Patients for Treatment With Targeted Tyrosine Kinase Inhibitors. In The Journal of Molecular Diagnostics (Vol. 20, Issue 2, pp. 129–159). Elsevier BV. https://doi.org/10.1016/j.jmoldx.2017.11.004
      (Update in Progress)

    21. Richards, S., Aziz, N., Bale, S. et al. Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology. Genet Med 17, 405–423 (2015). https://doi.org/10.1038/gim.2015.30

    22. Lyon, E., Temple-Smolkin, R. L., Hegde, M., Gastier-Foster, J. M., Palomaki, G. E., & Richards, C. S. (2022). An Educational Assessment of Evidence Used for Variant Classification. In The Journal of Molecular Diagnostics (Vol. 24, Issue 6, pp. 555–565). Elsevier BV. https://doi.org/10.1016/j.jmoldx.2021.12.014

    23. Lockwood, C. M., Borsu, L., Cankovic, M., Earle, J. S. L., Gocke, C. D., Hameed, M., Jordan, D., Lopategui, J. R., Pullambhatla, M., Reuther, J., Rumilla, K. M., Tafe, L. J., Temple-Smolkin, R. L., Terraf, P., & Tsimberidou, A. M. (2023). Recommendations for Cell-Free DNA Assay Validations. In The Journal of Molecular Diagnostics (Vol. 25, Issue 12, pp. 876–897). Elsevier BV. https://doi.org/10.1016/j.jmoldx.2023.09.004

    24. Molecular In My Pocket Cards (reviewed annually): https://www.amp.org/education/amp-review-resources/molecular-in-my-pocket-guides/

    25. Association for Molecular Pathology (AMP) Clinical Practice Guidelines: https://www.amp.org/clinical-practice/practice-guidelines/

    26. Bruford EA, Antonescu CR, Carroll AJ, Chinnaiyan A, Cree IA, Cross NCP, Dalgleish R, Gale RP, Harrison CJ, Hastings RJ, Huret JL, Johansson B, Le Beau M, Mecucci C, Mertens F, Verhaak R, Mitelman F. HUGO Gene Nomenclature Committee (HGNC) recommendations for the designation of gene fusions. Leukemia. 2021 Nov;35(11):3040-3043. doi: 10.1038/s41375-021-01436-6. Epub 2021 Oct 6. PMID: 34615987; PMCID: PMC8550944. https://pmc.ncbi.nlm.nih.gov/articles/PMC8550944/

    27. Louis DN, Perry A, Wesseling P, Brat DJ, Cree IA, Figarella-Branger D, Hawkins C, Ng HK, Pfister SM, Reifenberger G, Soffietti R, von Deimling A, Ellison DW. The 2021 WHO Classification of Tumors of the Central Nervous System: a summary. Neuro Oncol. 2021 Aug 2;23(8):1231-1251. doi: 10.1093/neuonc/noab106. PMID: 34185076; PMCID: PMC8328013.

    28. WHO Classification of Tumours Editorial Board. Central nervous system tumours. Lyon (France): International Agency for Research on Cancer; 2021. (WHO classification of tumours series, 5th ed.; vol. 6). https://publications.iarc.fr/601.

    29. International Consensus Classification of Myeloid Neoplasms: https://ashpublications.org/blood/article/140/11/1200/485730/International-Consensus-Classification-of-Myeloid

    30. International Consensus Classification of Mature Lymphoid Neoplasms: https://ashpublications.org/blood/article/140/11/1229/485458/The-International-Consensus-Classification-of

    31. WHO Classification of Tumours Editorial Board. Haematolymphoid tumours. Lyon (France): International Agency for Research on Cancer; forthcoming. (WHO classification of tumours series, 5th ed.; vol. 11). https://tumourclassification.iarc.who.int/chapters/63

    32. Pirmohamed M. Pharmacogenomics: current status and future perspectives. Nat Rev Genet. 2023 Jun;24(6):350-362. doi: 10.1038/s41576-022-00572-8. Epub 2023 Jan 27. PMID: 36707729.
    Neuropathology

    TUMORS

    1. Louis DN, Perry A, Wesseling P, Brat DJ, Cree IA, Figarella-Branger D, Hawkins C, Ng HK, Pfister SM, Reifenberger G, Soffietti R, von Deimling A, Ellison DW. The 2021 WHO Classification of Tumors of the Central Nervous System: a summary. Neuro Oncol. 2021 Aug 2;23(8):1231-1251. doi: 10.1093/neuonc/noab106. PMID: 34185076; PMCID: PMC8328013.

    2. WHO Classification of Tumours Editorial Board. Central nervous system tumours. Lyon (France): International Agency for Research on Cancer; 2021. (WHO classification of tumours series, 5th ed.; vol. 6). https://publications.iarc.fr/601.

    PITUITARY

    1. Asa SL, Mete O, Perry A, Osamura RY. Overview of the 2022 WHO Classification of Pituitary Tumors. Endocr Pathol. 2022 Mar;33(1):6-26. doi: 10.1007/s12022-022-09703-7. Epub 2022 Mar 15. PMID: 35291028.

    EPILEPSY

    1. Najm I, Lal D, Alonso Vanegas M, Cendes F, Lopes-Cendes I, Palmini A, Paglioli E, Sarnat HB, Walsh CA, Wiebe S, Aronica E, Baulac S, Coras R, Kobow K, Cross JH, Garbelli R, Holthausen H, Rössler K, Thom M, El-Osta A, Lee JH, Miyata H, Guerrini R, Piao YS, Zhou D, Blümcke I. The ILAE consensus classification of focal cortical dysplasia: An update proposed by an ad hoc task force of the ILAE diagnostic methods commission. Epilepsia. 2022 Aug;63(8):1899-1919. doi: 10.1111/epi.17301. Epub 2022 Jun 15. PMID: 35706131; PMCID: PMC9545778.

    2. Blümcke, I., Aronica, T.M., Armstrong, D.D., Bartolomei, F., Bernasconi, A., Bernasconi, N… (2013). International consensus classification of hippocampal sclerosis in temporal lobe epilepsy: a Task Force report from the ILAE Commission on Diagnostic Methods. Epilepsia, 54(7), 1315-1329.

    MUSCLE

    1. Nix JS, Moore SA. What Every Neuropathologist Needs to Know: The Muscle Biopsy. J Neuropathol Exp Neurol. 2020 Jul 1;79(7):719-733. doi: 10.1093/jnen/nlaa046. Erratum in: J Neuropathol Exp Neurol. 2021 Mar 22;80(4):387. PMID: 32529201; PMCID: PMC7304986.

    2. Dowling JJ, Weihl CC, Spencer MJ. Molecular and cellular basis of genetically inherited skeletal muscle disorders. Nat Rev Mol Cell Biol. 2021 Nov;22(11):713-732. doi: 10.1038/s41580-021-00389-z. Epub 2021 Jul 13. PMID: 34257452; PMCID: PMC9686310.

    NERVE

    1. Chkheidze R, Pytel P. What Every Neuropathologist Needs to Know: Peripheral Nerve Biopsy. J Neuropathol Exp Neurol. 2020 Apr 1;79(4):355-364. doi: 10.1093/jnen/nlaa012. PMID: 32167544.

    NEURODEGENERATION

    1. Montine TJ, Phelps CH, Beach TG, Bigio EH, Cairns NJ, Dickson DW, Duyckaerts C, Frosch MP, Masliah E, Mirra SS, Nelson PT, Schneider JA, Thal DR, Trojanowski JQ, Vinters HV, Hyman BT; National Institute on Aging; Alzheimer’s Association. National Institute on Aging-Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach. Acta Neuropathol. 2012 Jan;123(1):1-11. doi: 10.1007/s00401-011-0910-3. Epub 2011 Nov 20. PMID: 22101365; PMCID: PMC3268003.

    2. McKeith IG, Dickson DW, Lowe J, Emre M, O’Brien JT, Feldman H, Cummings J, Duda JE, Lippa C, Perry EK, Aarsland D, Arai H, Ballard CG, Boeve B, Burn DJ, Costa D, Del Ser T, Dubois B, Galasko D, Gauthier S, Goetz CG, Gomez-Tortosa E, Halliday G, Hansen LA, Hardy J, Iwatsubo T, Kalaria RN, Kaufer D, Kenny RA, Korczyn A, Kosaka K, Lee VM, Lees A, Litvan I, Londos E, Lopez OL, Minoshima S, Mizuno Y, Molina JA, Mukaetova-Ladinska EB, Pasquier F, Perry RH, Schulz JB, Trojanowski JQ, Yamada M; Consortium on DLB. Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium. Neurology. 2005 Dec 27;65(12):1863-72. doi: 10.1212/01.wnl.0000187889.17253.b1. Epub 2005 Oct 19. Erratum in: Neurology. 2005 Dec 27;65(12):1992. PMID: 16237129.

    3. Cairns NJ, Bigio EH, Mackenzie IR, Neumann M, Lee VM, Hatanpaa KJ, White CL 3rd, Schneider JA, Grinberg LT, Halliday G, Duyckaerts C, Lowe JS, Holm IE, Tolnay M, Okamoto K, Yokoo H, Murayama S, Woulfe J, Munoz DG, Dickson DW, Ince PG, Trojanowski JQ, Mann DM; Consortium for Frontotemporal Lobar Degeneration. Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration. Acta Neuropathol. 2007 Jul;114(1):5-22. doi: 10.1007/s00401-007-0237-2. Epub 2007 Jun 20. PMID: 17579875; PMCID: PMC2827877.

    4. Gilman S, Wenning GK, Low PA, Brooks DJ, Mathias CJ, Trojanowski JQ, Wood NW, Colosimo C, Dürr A, Fowler CJ, Kaufmann H, Klockgether T, Lees A, Poewe W, Quinn N, Revesz T, Robertson D, Sandroni P, Seppi K, Vidailhet M. Second consensus statement on the diagnosis of multiple system atrophy. Neurology. 2008 Aug 26;71(9):670-6. doi: 10.1212/01.wnl.0000324625.00404.15. PMID: 18725592; PMCID: PMC2676993.
    Pediatric Perinatal Pathology

    TRANSFUSION

    1. Sanchez, R., Sloan, S. R., Josephson, C. D., Ambruso, D. R., Hillyer, C. D., & O’Sullivan, P. (2010). Consensus recommendations of pediatric transfusion medicine objectives for clinical pathology residency training programs. Transfusion, 50(5), 1071–1078. https://doi.org/10.1111/j.1537-2995.2009.02549.x

    PERINATAL

    1. Khong, T. Y., Mooney, E. E., Ariel, I., Balmus, N. C., Boyd, T. K., Brundler, M. A., Derricott, H., Evans, M. J., Faye-Petersen, O. M., Gillan, J. E., Heazell, A. E., Heller, D. S., Jacques, S. M., Keating, S., Kelehan, P., Maes, A., McKay, E. M., Morgan, T. K., Nikkels, P. G., Parks, W. T., … Gordijn, S. J. (2016). Sampling and Definitions of Placental Lesions: Amsterdam Placental Workshop Group Consensus Statement. Archives of pathology & laboratory medicine, 140(7), 698–713. https://doi.org/10.5858/arpa.2015-0225-CC

    2. Hecht, J. L., Baergen, R., Ernst, L. M., Katzman, P. J., Jacques, S. M., Jauniaux, E., Khong, T. Y., Metlay, L. A., Poder, L., Qureshi, F., Rabban, J. T., 3rd, Roberts, D. J., Shainker, S., & Heller, D. S. (2020). Classification and reporting guidelines for the pathology diagnosis of placenta accreta spectrum (PAS) disorders: recommendations from an expert panel. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 33(12), 2382–2396. https://doi.org/10.1038/s41379-020-0569-1

    SOFT TISSUE

    1. WHO Classification of Tumours Editorial Board. Paediatric tumours. Lyon (France): International Agency for Research on Cancer; 2022. (WHO Classification of Tumours series, 5th ed.; vol. 7). https://publications.iarc.fr/608.

    2. ISSVA classification of vascular anomalies ©2025 International Society for the Study of Vascular Anomalies https://www.issva.org/classification

    GASTROINTESTINAL

    1. Ambartsumyan, L., Smith, C., & Kapur, R. P. (2019). Diagnosis of Hirschsprung Disease. Pediatric and Developmental Pathology, 23(1), 8–22. https://doi.org/10.1177/1093526619892351 Epub 2019 Dec 2. PMID: 31791203.

    2. Dellon ES et al. Updated International Consensus Diagnostic Criteria for Eosinophilic Esophagitis: Proceedings of the AGREE Conference. Gastroenterology. 2018 Oct;155(4):1022-1033.e10. doi: 10.1053/j.gastro.2018.07.009. Epub 2018 Sep 6. PMID: 30009819; PMCID: PMC6174113.

    OTHER

    1. CAP Pediatric Cancer Protocol Templates
      https://www.cap.org/protocols-and-guidelines/cancer-reporting-tools/cancer-protocol-templates

    2. Genest DR, Williams MA, Greene MF. Estimating the time of death in stillborn fetuses: I. Histologic evaluation of fetal organs; an autopsy study of 150 stillborns. Obstet Gynecol. 1992 Oct;80(4):575-84. PMID: 1383898.

    3. Genest DR. Estimating the time of death in stillborn fetuses: II. Histologic evaluation of the placenta; a study of 71 stillborns. Obstet Gynecol. 1992 Oct;80(4):585-92. PMID: 1407877.
    Respiratory Tract, Pleura, and Mediastinum
    1. WHO Classification of Tumours Editorial Board. Thoracic tumours. Lyon (France): International Agency for Research on Cancer; 2021. (WHO classification of tumours series, 5th ed.; vol. 5). https://publications.iarc.fr/595.

    2. Alarcon-Calderon A, Vassallo R, Yi ES, Ryu JH. Smoking-Related Interstitial Lung Diseases. Immunol Allergy Clin North Am. 2023 May;43(2):273-287. doi: 10.1016/j.iac.2023.01.007. Epub 2023 Mar 1. PMID: 37055089.

    3. Hua JT, Cool CD, Green FHY. Pathology and Mineralogy of the Pneumoconioses. Semin Respir Crit Care Med. 2023 Jun;44(3):327-339. doi: 10.1055/s-0043-1764406. Epub 2023 Mar 27. PMID: 36972614; PMCID: PMC11617341.

    4. Husain, A. N., Chapel, D. B., Attanoos, R., Beasley, M. B., Brcic, L., Butnor, K., Chirieac, L. R., Churg, A., Dacic, S., Galateau-Salle, F., Hiroshima, K., Hung, Y. P., Klebe, S., Krausz, T., Khoor, A., Litzky, L., Marchevsky, A., Nabeshima, K., Nicholson, A. G., Pavlisko, E. N., … Colby, T. V. (2024). Guidelines for Pathologic Diagnosis of Mesothelioma: 2023 Update of the Consensus Statement From the International Mesothelioma Interest Group. Archives of pathology & laboratory medicine, 148(11), 1251–1271. https://doi.org/10.5858/arpa.2023-0304-RA

    5. Moreira AL, Ocampo PSS, Xia Y, Zhong H, Russell PA, Minami Y, Cooper WA, Yoshida A, Bubendorf L, Papotti M, Pelosi G, Lopez-Rios F, Kunitoki K, Ferrari-Light D, Sholl LM, Beasley MB, Borczuk A, Botling J, Brambilla E, Chen G, Chou TY, Chung JH, Dacic S, Jain D, Hirsch FR, Hwang D, Lantuejoul S, Lin D, Longshore JW, Motoi N, Noguchi M, Poleri C, Rekhtman N, Tsao MS, Thunnissen E, Travis WD, Yatabe Y, Roden AC, Daigneault JB, Wistuba II, Kerr KM, Pass H, Nicholson AG, Mino-Kenudson M. A Grading System for Invasive Pulmonary Adenocarcinoma: A Proposal From the International Association for the Study of Lung Cancer Pathology Committee. J Thorac Oncol. 2020 Oct;15(10):1599-1610. doi: 10.1016/j.jtho.2020.06.001. Epub 2020 Jun 17. PMID: 32562873; PMCID: PMC8362286.

    6. Travis WD, Costabel U, Hansell DM, King TE Jr, Lynch DA, Nicholson AG, Ryerson CJ, Ryu JH, Selman M, Wells AU, Behr J, Bouros D, Brown KK, Colby TV, Collard HR, Cordeiro CR, Cottin V, Crestani B, Drent M, Dudden RF, Egan J, Flaherty K, Hogaboam C, Inoue Y, Johkoh T, Kim DS, Kitaichi M, Loyd J, Martinez FJ, Myers J, Protzko S, Raghu G, Richeldi L, Sverzellati N, Swigris J, Valeyre D; ATS/ERS Committee on Idiopathic Interstitial Pneumonias. An official American Thoracic Society/European Respiratory Society statement: Update of the international multidisciplinary classification of the idiopathic interstitial pneumonias. Am J Respir Crit Care Med. 2013 Sep 15;188(6):733-48. doi: 10.1164/rccm.201308-1483ST. PMID: 24032382; PMCID: PMC5803655.
    Soft Tissue, Bones, and Joints
    1. WHO Classification of Tumours Editorial Board. Soft tissue and bone tumours. Lyon (France): International Agency for Research on Cancer; 2020. (WHO classification of tumours series, 5th ed.; vol. 3). https://publications.iarc.fr/588.
    Urinary System

    Kidney

    1. Han, M. H., & Kim, Y. J. (2016). Practical Application of Columbia Classification for Focal Segmental Glomerulosclerosis. BioMed research international, 2016, 9375753. https://doi.org/10.1155/2016/9375753

    2. Moch, H., Amin, M. B., Berney, D. M., Compérat, E. M., Gill, A. J., Hartmann, A., … & Netto, G. J. (2022). The 2022 World Health Organization classification of tumours of the urinary system and male genital organs—part A: renal, penile, and testicular tumours. European urology.

    3. WHO Classification of Tumours Editorial Board. Urinary and male genital tumours. Lyon (France): International Agency for Research on Cancer; 2022. (WHO classification of tumours series, 5th ed.; vol. 8). https://publications.iarc.fr/610.

    Urothelial Tract and Bladder

    1. Moch, H., Amin, M. B., Berney, D. M., Compérat, E. M., Gill, A. J., Hartmann, A., … & Netto, G. J. (2022). The 2022 World Health Organization classification of tumours of the urinary system and male genital organs—part A: renal, penile, and testicular tumours. European urology.

    2. WHO Classification of Tumours Editorial Board. Urinary and male genital tumours. Lyon (France): International Agency for Research on Cancer; 2022. (WHO classification of tumours series, 5th ed.; vol. 8). https://publications.iarc.fr/610.

    Clinical Pathology (CP)


    General Clinical Pathology

    Smith, B. R., Wells, A., Alexander, C. B., Bovill, E., Campbell, S., Dasgupta, A., Fung, M., Haller, B., Howe, J. G., Parvin, C., Peerschke, E., Rinder, H., Spitalnik, S., Weiss, R., & Wener, M. (2006). Curriculum content and evaluation of resident competency in clinical pathology (laboratory medicine): a proposal. Clinical Chemistry, 52(6), 917–949. https://doi.org/10.1373/clinchem.2005.066076

    General CP with Subspecialty Areas Represented

    Accreditation Checklists
    https://www.cap.org/laboratory-improvement/accreditation/accreditation-checklists

    Hematopathology

    1. World Health Organization. WHO Classification of Tumours: Haematolymphoid Tumours. 5th edition. Lyon, France: International Agency for Research on Cancer, 2024.

    2. James PD, Connell NT, Ameer B, Di Paola J, Eikenboom J, Giraud N, Haberichter S, Jacobs-Pratt V, Konkle B, McLintock C, McRae S, R Montgomery R, O’Donnell JS, Scappe N, Sidonio R, Flood VH, Husainat N, Kalot MA, Mustafa RA. ASH ISTH NHF WFH 2021 guidelines on the diagnosis of von Willebrand disease. Blood Adv. 2021 Jan 12;5(1):280-300. doi: 10.1182/bloodadvances.2020003265. PMID: 33570651; PMCID: PMC7805340.

    3. Hayward CP, Moffat KA, Raby A, Israels S, Plumhoff E, Flynn G, Zehnder JL. Development of North American consensus guidelines for medical laboratories that perform and interpret platelet function testing using light transmission aggregometry. Am J Clin Pathol. 2010 Dec;134(6):955-63. doi: 10.1309/AJCP9V3RRVNZMKDS. PMID: 21088160.


    4. Zheng XL, Vesely SK, Cataland SR, Coppo P, Geldziler B, Iorio A, Matsumoto M, Mustafa RA, Pai M, Rock G, Russell L, Tarawneh R, Valdes J, Peyvandi F. ISTH guidelines for the diagnosis of thrombotic thrombocytopenic purpura. J Thromb Haemost. 2020 Oct;18(10):2486-2495. doi: 10.1111/jth.15006. Epub 2020 Sep 11. Erratum in: J Thromb Haemost. 2021 May;19(5):1381. doi: 10.1111/jth.15304. PMID: 32914582; PMCID: PMC8146131.


    5. Devreese KMJ, Bertolaccini ML, Branch DW, de Laat B, Erkan D, Favaloro EJ, Pengo V, Ortel TL, Wahl D, Cohen H. An update on laboratory detection and interpretation of antiphospholipid antibodies for diagnosis of antiphospholipid syndrome: guidance from the ISTH-SSC Subcommittee on Lupus Anticoagulant/Antiphospholipid Antibodies. J Thromb Haemost. 2025 Feb;23(2):731-744. doi: 10.1016/j.jtha.2024.10.022. Epub 2024 Nov 5. PMID: 39510414.




    Blood Banking/Transfusion Medicine
    1. AABB Technical Manual (current edition)

    2. AABB Standards (current edition): https://www.aabb.org/standards-accreditation/standards/purchase-standards

    3. FACT Standards for Hematopoietic Cellular Therapy https://www.factglobal.org/standards/hct-standards/

    4. CAP Transfusion Medicine Checklist https://documents.cap.org/documents/2024-Checklist-Summary.pdf?_gl=1*rb35z6*_ga*OTU1MDU2Nzc1LjE3Mzc4NDYxNTk.*_ga_97ZFJSQQ0X*MTczODk0OTg5OS4yLjEuMTczODk0OTk4Mi4wLjAuMA

    5. FDA Blood Guidances https://www.fda.gov/vaccines-blood-biologics/biologics-guidances/blood-guidances

    6. Connelly-Smith, L., Alquist, C. R., Aqui, N. A., Hofmann, J. C., Klingel, R., Onwuemene, O. A., … Dunbar, N. M. (2023). Guidelines on the Use of Therapeutic Apheresis in Clinical Practice – Evidence‐Based Approach from the Writing Committee of the American Society for Apheresis: The Ninth Special Issue. 38(2), 77–278. https://doi.org/10.1002/jca.22043 PMID: 37017433.

    7. National Healthcare Safety Network Biovigilance Component Hemovigilance Module Surveillance Protocol https://www.cdc.gov/nhsn/pdfs/biovigilance/bv-hv-protocol-current.pdf

    8. Circular of Information for the Use of Human Blood and Blood Components – Watermarked Version (aabb.org). https://www.aabb.org/docs/default-source/default-document-library/resources/circular-of-information-watermark.pdf

    9. Circular of Information for the Use of Cellular Therapy Products https://www.aabb.org/docs/default-source/default-document-library/resources/ct-circular-of-information.pdf?sfvrsn=7d15e2b9_7

    Chemical Pathology
    1. CLSI. Liquid Chromatography-Mass Spectrometry Methods. 2nd ed. CLSI guideline C62. Clinical and Laboratory Standards Institute; 2022.

    2. CLSI. Sweat Testing: Specimen Collection and Quantitative Chloride Analysis. 4th ed. CLSI guideline C34. Wayne, PA: Clinical and Laboratory Standards Institute; 2019.

    3. CLSI. Analysis of Body Fluids in Clinical Chemistry. 2nd ed. CLSI guideline C49. Wayne, PA: Clinical and Laboratory Standards Institute; 2018.

    4. CLSI. Toxicology and Drug Testing in the Medical Laboratory. 3rd ed. CLSI guideline C52. Wayne, PA: Clinical and Laboratory Standards Institute; 2017.

    5. CLSI EP12-ED3IG:2023 Verification of Performance of a Qualitative, Binary Output Examination Implementation Guide. Wayne, PA: Clinical and Laboratory Standards Institute

    6. CLSI. Evaluation of Total Analytical Error for Quantitative Medical Laboratory Measurement Procedures. 2nd ed. CLSI guideline EP21. Wayne, PA: Clinical and Laboratory Standards Institute; 2016.

    7. Keren, D. F., Bocsi, G., Billman, B. L., Etzell, J., Faix, J. D., Kumar, S., Lipe, B., McCudden, C., Montgomery, R., Murray, D. L., Rai, A. J., Redondo, T. C., Souter, L., Ventura, C. B., & Ansari, M. Q. (2022). Laboratory Detection and Initial Diagnosis of Monoclonal Gammopathies. Archives of pathology & laboratory medicine, 146(5), 575–590. https://doi.org/10.5858/arpa.2020-0794-CP

    8. American Diabetes Association Professional Practice Committee; 2. Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes—2022. Diabetes Care 1 January 2022; 45 (Supplement_1): S17–S38. https://doi.org/10.2337/dc22-S002

    9. Laboratory Detection and Initial Diagnosis of Monoclonal Gammopathies.
      Keren DF, Bocsi G, Billman BL, Etzell J, Faix JD, Kumar S, Lipe B, McCudden C, Montgomery R, Murray DL, Rai AJ, Redondo TC, Souter L, Ventura CB, Ansari MQ.
      Arch Pathol Lab Med. 2022 May 1;146(5):575-590. doi: 10.5858/arpa.2020-0794-CP.
      PMID: 34347866

    10. Synoptic reporting for protein electrophoresis and immunofixation.
      McCudden CR, Booth RA, Lin DCC, McCurdy A, Rupani N, Kew A.
      Clin Biochem. 2018 Jan;51:21-28. doi: 10.1016/j.clinbiochem.2017.09.020. Epub 2017 Sep 28.
      PMID: 28964759 Review. No abstract available.

    11. Fourth Universal Definition of Myocardial Infarction (2018).
      Thygesen K, Alpert JS, Jaffe AS, Chaitman BR, Bax JJ, Morrow DA, White HD; Executive Group on behalf of the Joint European Society of Cardiology (ESC)/American College of Cardiology (ACC)/American Heart Association (AHA)/World Heart Federation (WHF) Task Force for the Universal Definition of Myocardial Infarction.
      J Am Coll Cardiol. 2018 Oct 30;72(18):2231-2264. doi: 10.1016/j.jacc.2018.08.1038. Epub 2018 Aug 25.
      PMID: 30153967 Review. No abstract available.

    12. High-Sensitivity Cardiac Troponin and the 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guidelines for the Evaluation and Diagnosis of Acute Chest Pain.
      Sandoval Y, Apple FS, Mahler SA, Body R, Collinson PO, Jaffe AS; International Federation of Clinical Chemistry and Laboratory Medicine Committee on the Clinical Application of Cardiac Biomarkers.
      Circulation. 2022 Aug 16;146(7):569-581. doi: 10.1161/CIRCULATIONAHA.122.059678. Epub 2022 Jul 1.

    13. Rajkumar SV, Dimopoulos MA, Palumbo A, Blade J, Merlini G, Mateos MV, Kumar S, Hillengass J, Kastritis E, Richardson P, Landgren O, Paiva B, Dispenzieri A, Weiss B, LeLeu X, Zweegman S, Lonial S, Rosinol L, Zamagni E, Jagannath S, Sezer O, Kristinsson SY, Caers J, Usmani SZ, Lahuerta JJ, Johnsen HE, Beksac M, Cavo M, Goldschmidt H, Terpos E, Kyle RA, Anderson KC, Durie BG, Miguel JF. International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma. Lancet Oncol. 2014 Nov;15(12):e538-48. doi: 10.1016/S1470-2045(14)70442-5. Epub 2014 Oct 26. PMID: 25439696.

    14. Kumar S, Paiva B, Anderson KC, Durie B, Landgren O, Moreau P, Munshi N, Lonial S, Bladé J, Mateos MV, Dimopoulos M, Kastritis E, Boccadoro M, Orlowski R, Goldschmidt H, Spencer A, Hou J, Chng WJ, Usmani SZ, Zamagni E, Shimizu K, Jagannath S, Johnsen HE, Terpos E, Reiman A, Kyle RA, Sonneveld P, Richardson PG, McCarthy P, Ludwig H, Chen W, Cavo M, Harousseau JL, Lentzsch S, Hillengass J, Palumbo A, Orfao A, Rajkumar SV, Miguel JS, Avet-Loiseau H. International Myeloma Working Group consensus criteria for response and minimal residual disease assessment in multiple myeloma. Lancet Oncol. 2016 Aug;17(8):e328-e346. doi: 10.1016/S1470-2045(16)30206-6. PMID: 27511158.

    15. Chronic Kidney Disease Guidance. https://kdigo.org/wp-content/uploads/2017/02/KDIGO-2024-CKD-Guideline-Executive-Summary.pdf
    Clinical Informatics
    1. Pathology Informatics Essentials for Residents (PIER): https://www.apcprods.org/m-pier
    Hematopathology
    1. The International Consensus Classification of Myeloid and Lymphoid Neoplasms. 1st ed. Arber DA, Borowitz MJ, Cook JR, de Leval L, Goodlad JR, Hasserjian RP, et al., editors. Philadelphia: Wolters Kluwer; 2025.


    2. Li, W. (2022). The 5th Edition of the World Health Organization Classification of Hematolymphoid Tumors. Exon Publications, 1-21.

    3. Kavus, H., Ding, Y., & Dhesi, M. (2023). Updates in Immunohistochemistry for Hematopoietic and Lymphoid Neoplasms. Archives of pathology & laboratory medicine, 10.5858/arpa.2022-0465-RA. Advance online publication. https://doi.org/10.5858/arpa.2022-0465-RA

    4. Rajkumar SV, Dimopoulos MA, Palumbo A, Blade J, Merlini G, Mateos MV, Kumar S, Hillengass J, Kastritis E, Richardson P, Landgren O, Paiva B, Dispenzieri A, Weiss B, LeLeu X, Zweegman S, Lonial S, Rosinol L, Zamagni E, Jagannath S, Sezer O, Kristinsson SY, Caers J, Usmani SZ, Lahuerta JJ, Johnsen HE, Beksac M, Cavo M, Goldschmidt H, Terpos E, Kyle RA, Anderson KC, Durie BG, Miguel JF. International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma. Lancet Oncol. 2014 Nov;15(12):e538-48. doi: 10.1016/S1470-2045(14)70442-5. Epub 2014 Oct 26. PMID: 25439696.

    5. Kumar S, Paiva B, Anderson KC, Durie B, Landgren O, Moreau P, Munshi N, Lonial S, Bladé J, Mateos MV, Dimopoulos M, Kastritis E, Boccadoro M, Orlowski R, Goldschmidt H, Spencer A, Hou J, Chng WJ, Usmani SZ, Zamagni E, Shimizu K, Jagannath S, Johnsen HE, Terpos E, Reiman A, Kyle RA, Sonneveld P, Richardson PG, McCarthy P, Ludwig H, Chen W, Cavo M, Harousseau JL, Lentzsch S, Hillengass J, Palumbo A, Orfao A, Rajkumar SV, Miguel JS, Avet-Loiseau H. International Myeloma Working Group consensus criteria for response and minimal residual disease assessment in multiple myeloma. Lancet Oncol. 2016 Aug;17(8):e328-e346. doi: 10.1016/S1470-2045(16)30206-6. PMID: 27511158.

    Medical Microbiology

    Clinical Pathology Resident Level Appropriate

    1. Miller JM, Binnicker MJ, Campbell S, Carroll KC, Chapin KC, Gonzalez MD, Harrington A, Jerris RC, Kehl SC, Leal SM Jr, Patel R, Pritt BS, Richter SS, Robinson-Dunn B, Snyder JW, Telford S 3rd, Theel ES, Thomson RB Jr, Weinstein MP, Yao JD. Guide to Utilization of the Microbiology Laboratory for Diagnosis of Infectious Diseases: 2024 Update by the Infectious Diseases Society of America (IDSA) and the American Society for Microbiology (ASM). Clin Infect Dis. 2024 Mar 5:ciae104. doi: 10.1093/cid/ciae104. Epub ahead of print. PMID: 38442248. Guide to Utilization of the Microbiology Laboratory for Diagnosis of Infectious Diseases: 2024 Update by the Infectious Diseases Society of America (IDSA) and the American Society for Microbiology (ASM)

    2. CLSI Document: M100: http://em100.edaptivedocs.net/dashboard.aspx (Log in required) Note: Not for memorization but for the ability to use

    3. CLSI M35 Abbreviated Identification of Bacteria and Yeast (See current edition)

    4. Burd, E. M. (2010). Validation of Laboratory-Developed Molecular Assays for Infectious Diseases. Clinical Microbiology Reviews, 23(3), 550–576. https://doi.org/10.1128/cmr.00074-09

    5. Centers for Disease Control and Prevention. (2024, June 13). DPDx – Resources for Parasitic Diseases. https://www.cdc.gov/dpdx/reference.html. 

    6. Guarner J, Brandt ME. Histopathologic diagnosis of fungal infections in the 21st century. Clin Microbiol Rev. 2011;24(2):247-280. doi:10.1128/CMR.00053-10 ()https://pmc.ncbi.nlm.nih.gov/articles/PMC3122495/

    7. CDC: Sexually Transmitted Infections Treatment Guidelines, 2021. https://www.cdc.gov/std/treatment-guidelines/STI-Guidelines-2021.pdf

    8. Pritt BS. Parasitology Benchtop Reference G

    9. Clinical Laboratory Improvement Amendments (CLIA). Proficiency Testing and PT Referral. https://www.cms.gov/regulations-and-guidance/legislation/clia/downloads/cliabrochure8.pdf

    Medical Microbiology Fellow Level Additional Recommendations

    1. CLSI MM18. Interpretive Criteria for Identification of Bacteria and Fungi by Targeted DNA Sequencing.

    2. Mathison BA, Pritt BS. Arthropod Benchtop Reference Guide

    3. Pathology of infectious diseases ; Gary W. Procop, Bobbi S. Pritt. (eds.) Philadelphia, PA : Elsevier/Saunders; 2015. Library Catalog ; MMS ID 9916285073406676; ISBN 9781437707625; NLM Unique ID 101628507

    4. Diagnostic Pathology: Infectious Diseases. Isaac H. Soloman, Dan Milner (eds.) Philadelphia, PA : Elsevier. 2024. ISBN-13: 978-0443124778. 5. Tamma, P. D., Heil, E. L., Justo, J. A., Mathers, A. J., Satlin, M. J., & Bonomo, R. A. (2024). Infectious Diseases Society of America 2024 Guidance on the Treatment of Antimicrobial-Resistant Gram-Negative Infections. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, ciae403. Advance online publication. https://doi.org/10.1093/cid/ciae403